Linda,
My magic numbers have been 15-20 students, but it certainly depends on the course, content, level, etc. Transitioning to online teaching can be a bit of a challenge at times, but one thing to always keep in mind....change is a constant! I change aspects of my online courses every semester. The opening posts, discussions, and course expectations are not anywhere near the same as they were the first time I taught the course. A couple of important things to remember: you will typically need more details regarding course expectations and assignments than the traditional classroom. Students in a traditional class will ask you subtle clarification questions on these items in class, but in the online classroom many students just make assumptions - which may be right or wrong. Be positive and constructive in your grading, and provide "details" - rubrics for assignments help tremendously. Read some of the other expectations posts about what others include, such as: grading, communication, assignments, due dates, re-do policies, etc. Many folks include a beginning discussion for you and the students to share about yourselves to connect you all - build a sense of community. I hope this helps.
Herbert Brown III