Today’s teachers face many challenges in the classroom. We live in an era where schools are accountable for the learning of all students (regardless of their background). Teachers are expected to provide a rigorous and relevant core program while also providing supplemental and intensive levels of support for students whose needs are not being met by core. This includes students who are struggling to meet minimum competencies as well as students who have instructional needs that extend beyond grade level expectations. To ensure that all students are receiving the instruction they need to be successful, it is important to consider the research and best practice regarding teaching for learner differences.